Therapeutic indications
The raloxifene contained in Evista is used by women to prevent and treat bone loss (osteoporosis) after menopause. It slows down bone loss and helps keep bones strong so they are less likely to break.
Raloxifene may also reduce the chance of developing a certain type of breast cancer (invasive breast cancer) after menopause.
Raloxifene is not an estrogenic hormone, but acts like estrogen in certain parts of the body, such as the bones. In other parts of the body (uterus and breasts), raloxifene acts as an estrogen blocker. It does not relieve menopausal symptoms such as hot flashes. Raloxifene belongs to a class of drugs known as selective estrogen receptor modulators. Evista should not be used before menopause.
How to take Evista
Evista is taken by mouth with or without food as directed by a physician, usually once a day. Take this medicine regularly, preferably at the same time each day.
Swallow the tablet whole. Do not crush or chew as it has a bitter taste. Make sure you have enough calcium and vitamin D in your diet. Ask your doctor or pharmacist if you need to take calcium and vitamin D supplements.
Because this medicine can be absorbed through the skin and lungs and may harm an unborn baby, women who are or may become pregnant should not handle this medicine or breathe in dust from the tablets.
Side effects
You may experience hot flashes or leg cramps. If any of these effects persist or worsen, tell your doctor or pharmacist immediately.
Remember that your doctor has prescribed this medicine because he or she has decided that the benefit to you is greater than the risk of side effects. Many people using this drug do not have serious side effects.
Get medical help right away if you have any very serious side effects, including: signs of a blood clot (pain, swelling, redness, difficulty breathing, coughing up blood), changes such as blurred vision, symptoms of a stroke (weakness on one side of the body, difficulty speaking, sudden changes in vision, confusion).
A very serious allergic reaction to this medicine is rare. Seek immediate medical attention if you notice any signs of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, difficulty breathing.
Contraindication
Drug interactions can change how your medicine works or increase the risk of serious side effects.
Some products that may interact with this drug (Evista) include: bile acid sequestering resins (such as cholestyramine, colestipol), estrogens, tibolone.
Evista and raloxifene may interfere with some lab tests, causing false results. Make sure lab staff and all your doctors know you are taking this medicine.
Before taking raloxifene, tell your doctor or pharmacist if you are allergic to it or have any other allergies. Evista may contain inactive ingredients that may cause allergic reactions or other problems.
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