MANINIL (Glibenclamide), 1.75, 120

The drug is a drug for the treatment of non-insulin dependent diabetes in adults (type 2 diabetes mellitus).
The drug is used to reduce too high blood sugar levels in adult patients with diabetes (type 2 diabetes) when consistent adherence to the recommended diet appropriate for diabetes, weight loss if being overweight and physical activity alone do not provide adequate control of sugar levels in blood. blood sugar level.
The drug can be used alone (monotherapy) or in combination with metformin.
contraindication
The drug should not be taken
if you are allergic to glibenclamide
if you are allergic to any of the other ingredients of this medicine
if you are allergic to sulfonylurea derivatives, sulfonamides, sulfa diuretics and probenecid, as cross-reactions are possible
in the following cases of diabetes when insulin is required:
Insulin-dependent diabetes (type 1 diabetes mellitus), metabolic disorders in diabetes such as B. Hyperacidity of the blood (diabetic ketoacidosis), preliminary stages of coma and coma, and removal of the pancreas
if treatment with this medicine is no longer effective for non-insulin dependent diabetes (type 2 diabetes).
with severe liver dysfunction
with severe renal impairment
patients treated with bosentan.
Dosage of MANINIL 1.75
Always take this medicine exactly as your doctor has told you. Check with your doctor or pharmacist if you are not sure.
Dosage, even when switching from another blood sugar-lowering medication, will be determined by your doctor, taking into account your diabetes-friendly diet and blood and urine sugar control.
Film-coated tablets with an active ingredient content of 1 mg, as well as glibenclamide 3.5 mg and 5 mg are also available for individual adjustment of the required maintenance dose.
Unless otherwise prescribed by a physician, the usual dose is:
initial setup
Treatment should be started gradually with the lowest possible dosage:
1 (to 2) tablets (equivalent to 1.75–3.5 mg of glibenclamide) per day.
If this does not reduce blood sugar sufficiently, your doctor will gradually increase the dose – at intervals of a few days to about a week – up to the required daily dose.
up to a maximum of 6 tablets (equivalent to 10.5 mg glibenclamide) per day.
Switching from other medicines to lower blood sugar
If you are switching from another oral diabetes medicine to this medicine, your dosage should start with:
1 (to 2) tablets (equivalent to 1.75–3.5 mg of glibenclamide) per day.
If the dose exceeds 3 tablets per day, a dosage of glibenclamide 3.5 mg per tablet is recommended.
dose adjustment
During therapy, the need for glibenclamide may decrease. Your doctor will decide if your diss can be reduced.
If you are elderly, frail or debilitated, or if you have impaired kidney or liver function or are prone to hypoglycemia for other reasons, you should take a lower dose at the beginning and during treatment to reduce the risk of hypoglycemia. Your dose may also need to be adjusted if your weight or lifestyle changes.
Combination with other drugs to lower blood sugar
Under certain circumstances, additional administration of glitazones (rosiglitazone, pioglitazone) may be indicated.
This medicine can also be combined with other non-insulin releasing medicines used to treat diabetes (guar gum or acarbose).
If insulin production is reduced (the onset of secondary insufficiency), combination treatment with insulin can be tried. However, if insulin secretion in the body stops completely, treatment with insulin alone (insulin monotherapy) is indicated.
Please talk to your doctor or pharmacist if you have the impression that the medicine is too strong or too weak.
duration of use
Your doctor will decide how long you should use it.
If you take more than you should
Acute significant overdose of the drug, as well as the use of slightly overestimated doses for a long period of time, can lead to severe, persistent and possibly life-threatening hypoglycemia.
You can treat mild hypoglycemia yourself by eating sugar, high-sugar foods, or sugary drinks. This is why you should always carry 20 grams of glucose with you. If you are unable to resolve low blood sugar immediately on your own, call your doctor/ER immediately.
Even if hypoglycemia is initially treated successfully, it can recur. Contact your doctor.
If you forget to take a dose
Never take a double dose to make up for a missed dose, continue as directed.
If you stop taking it
You should not interrupt your treatment on your own or change your dose or diet
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